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We've been independently owned and the thoughts expressed Listed here are our very own. All editorial articles is published without having prejudice or bias, regardless of sponsor or affiliate associations. Browse more about our approach.We shown that, in distinction to classical opioid receptors, ACKR3 does not bring about classical G protein sign
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Gene expression analysis disclosed that ACKR3 is very expressed in quite a few brain locations akin to crucial opioid action facilities. Moreover, its expression concentrations are often greater than All those of classical opioid receptors, which even more supports the physiological relevance of its noticed in vitro opioid peptide scavenging abilit
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